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MSN,RN,CDE
World's First View of Type 1 Diabetes as It Unfolds/ must read
Section:  General Diabetes

"Researchers at the La Jolla Institute for Allergy & Immunology have created the first cellular movies showing the destruction underlying type 1 diabetes in real-time in mouse models. This detailed, dynamic view will provide the worldwide scientific community insights into this disease process as never before possible and may profoundly affect future directions in type 1 diabetes research.

A paper on the team's scientific findings, along with the cellular movies taken by the researchers, were published online December 1 in the Journal of Clinical Investigation. The movies are freely available and can be seen at: http://www.jci.org/articles/view/59285 (movie links at end of paper). Ken Coppieters, Ph.D., formerly of the La Jolla Institute and now at Ghent University, Belgium, is first author on the study. Dr. von Herrath is senior author.

"This live imaging of the white blood cells that cause diabetes is quite remarkable," said George Eisenbarth, M.D., Ph.D., a prominent type 1 diabetes researcher and executive director of the Barbara Davis Center for Childhood Diabetes in Colorado. "These images provide critical information about the disease process, in particular showing us the reasons why the beta cell destruction (underlying type 1 diabetes) occurs very slowly over time. Such information may enable new approaches to stop the destruction process, with the ultimate goal being prevention."

Please read the article in full here: http://www.sciencedaily.com/releases/2011/12/111201125147.htm

Thank you. Isabella Wiznitzer ,RN/CDE

MEMBER COMMENTS
Re: World's First View of Type 1 Diabetes as It Unfolds/ must read

Isabella,

Thank you.  The article was fascinating but I couldn't access the movie.  Do you know how I can get access to that?  Thanks for sharing this.

Re: World's First View of Type 1 Diabetes as It Unfolds/ must read

Hello Donna!
Please go to : http://www.jci.org/articles/view/59285  . Scroll all the way down to Supplemental Data and click on Supplemental videos 1-through 8. They are fastinating! Thank you. Isabella Wiznitzer,RN/CDE

Re: World's First View of Type 1 Diabetes as It Unfolds/ must read

Thanks, Isabella
The article is extremely interesting. I was able to view the videos, but there was no narrative with them. Did you get a narrative with the video or is there something wrong with way I accessed it

Re: World's First View of Type 1 Diabetes as It Unfolds/ must read

Patricia, some basic facts pertaining to the videos are discussed in Figures 1-8 in the article. There was no narrative, unfortunately. Thanks. Isabella Wiznitzer,RN/CDE